Publications (Peer-reviewed & Preprint)

2024

Ozdemir C, Olaimat MA, Vashishath Y, Bozdag S, & Alzheimer’s Disease Neuroimaging Initiative. IGCN: Integrative Graph Convolutional Networks for Multi-modal Data. arXiv; 2024 https://doi.org/10.48550/arXiv.2401.17612

Olaimat MA, Bozdag S. & Alzheimer’s Disease Neuroimaging Initiative TA-RNN: an Attention-based Time-aware Recurrent Neural Network Architecture for Electronic Health Records. arXiv; 2024 https://doi.org/10.48550/arXiv.2401.14694

2023

Akhavan Aghdam, M., Bozdag, S., Saeed, F., & Alzheimer’s Disease Neuroimaging Initiative. (2023). PVTAD: Alzheimer’s Disease Diagnosis Using Pyramid Vision Transformer Applied To White Matter Of T1-Weighted Structural MRI Data. bioRxiv, 2023-11.

Zitnik M, Li MM, Wells A, Glass K, Gysi DM, Krishnan A, Murali TM, Radivojac P, Roy S, Baudot A, Bozdag S, Chen DZ, Cowen L, Devkota K, Gitter A, Gosline S, Gu P, Guzzi PH, Huang H, Jiang M, Kesimoglu ZN, Koyuturk M, Ma J, Pico AR, Pržulj N, Przytycka TM, Raphael BJ, Ritz A, Sharan R, Shen Y, Singh M, Slonim DK, Tong H, Yang XH, Yoon BJ, Yu H, Milenković T. Current and future directions in network biology. arXiv; 2023. http://arxiv.org/abs/2309.08478.

Z. N. Kesimoglu and S. Bozdag, “SUPREME: multiomics data integration using graph convolutional networks,” NAR Genomics and Bioinformatics, vol. 5, no. 2, p. lqad063, Mar. 2023, doi: 10.1093/nargab/lqad063.

S. S. Madugula, S. Pandey, S. Amalapurapu, and S. Bozdag, “NRPreTo: A Machine Learning-Based Nuclear Receptor and Subfamily Prediction Tool,” ACS Omega, May 2023, https://doi.org/10.1021/acsomega.3c00286.

Z. N. Kesimoglu & S. Bozdag (2023). GRAF: Graph Attention-aware Fusion Networks. arXiv preprint arXiv:2303.16781. https://doi.org/10.48550/arXiv.2303.16781

M. Al Olaimat, J. Martinez, F. Saeed, S. Bozdag, and Alzheimer’s Disease Neuroimaging Initiative, “PPAD: a deep learning architecture to predict progression of Alzheimer’s disease,” (ISMB/ECCB 2023) Bioinformatics, vol. 39, no. Supplement_1, pp. i149–i157, Jun. 2023, doi: 10.1093/bioinformatics/btad249.

2022

T. Yang, M. A. Al-Duailij, S. Bozdag and F. Saeed, Classification of Autism Spectrum Disorder Using rs-fMRI data and Graph Convolutional Networks, 2022 IEEE International Conference on Big Data (Big Data), Osaka, Japan, 2022, pp. 3131-3138, https://doi.org/10.1109/BigData55660.2022.10021070

Bose B, Bozdag S. Finding the best cell lines across pan-cancer to use in pre-clinical research as a proxy for patient tumor samples considering immune cells, multi-omics, and cancer pathways. bioRxiv; 2022 https://doi.org/10.1101/2022.12.18.520831

Kleven AD, Middleton AH, Kesimoglu ZN, Slagel IC, Creager AE, Hanson R, Bozdag S, Edelstein AI (2022). Do In-Hospital Rothman Index Scores Predict Postdischarge Adverse Events and Discharge Location After Total Knee Arthroplasty?. The Journal of Arthroplasty, 37(4), 668-673. https://doi.org/10.1016/j.arth.2021.12.022

Bose B, Moravec M, Bozdag S. Computing microRNA-gene interaction networks in pan-cancer using miRDriver. Sci Rep. Nature Publishing Group; 2022 Mar 8;12(1):3717. https://doi.org/10.1038/s41598-022-07628-z

Creager, A. E., Kleven, A. D., Kesimoglu, Z. N., Middleton, A. H., Holub, M. N., Bozdag, S., & Edelstein, A. I. (2022). The Impact of Pre-Operative Healthcare Utilization on Complications, Readmissions, and Post-Operative Healthcare Utilization Following Total Joint Arthroplasty. The Journal of Arthroplasty, 37(3), 414-418. https://doi.org/10.1016/j.arth.2021.11.018

2021

Dursun C, Kwitek A, Bozdag S. PhenoGeneRanker: Gene and Phenotype Prioritization Using Multiplex Heterogeneous Networks. IEEE/ACM Trans Comput Biol Bioinform. 2021 Jul 20;PP. PMID: 34283720 https://doi.org/10.1109/TCBB.2021.3098278

Kesimoglu ZN, Bozdag S. Crinet: A computational tool to infer genome-wide competing endogenous RNA (ceRNA) interactions. PLoS One. 2021;16(5):e0251399. PMCID: PMC8118266 https://doi.org/10.1371/journal.pone.0251399

2020

Milali, M. P., Kiware, S. S., Govella, N. J., Okumu, F., Bansal, N., Bozdag, S., … Povinelli, R. J. (2020). An autoencoder and artificial neural network-based method to estimate parity status of wild mosquitoes from near-infrared spectra. PLOS ONE15(6), e0234557. https://doi.org/10.1371/journal.pone.0234557

Dursun C, Smith JR, Hayman GT, Kwitek AE, Bozdag S. NECo: A node embedding algorithm for multiplex heterogeneous networks. 2020 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). 2020. p. 146–149. https://doi.org/10.1109/BIBM49941.2020.9313595

Do D, Bozdag S. CanMod: A computational model to identify co-regulatory modules in cancer. Proceedings of the 11th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics . New York, NY, USA: Association for Computing Machinery; 2020. p. 1–10. https://doi.org/10.1145/3388440.3415586

Bose B, Bozdag S. CTDPathSim: Cell line-tumor deconvoluted pathway-based similarity in the context of precision medicine in cancer. Proceedings of the 11th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics. New York, NY, USA: Association for Computing Machinery; 2020. p. 1–10.  https://doi.org/10.1145/3388440.3412456

2019

Stamm, K., Tomita-Mitchell, A., & Bozdag, S. (2019). GSEPD: a Bioconductor package for RNA-seq gene set enrichment and projection display. BMC Bioinformatics20(1), 115. https://doi.org/10.1186/s12859-019-2697-5

Jain, N., Ahamed, S. I., Bozdag, S., Dolan, B. K., McVey, A. J., Willar, K. S., … Hecke, A. V. V. (2019). Have It, Know It, but Don’t Show It: Examining Physiological Arousal, Anxiety, and Facial Expressions over the Course of a Social Skills Intervention for Autistic Adolescents. BioRxiv, 582676. https://doi.org/10.1101/582676

Bose, B., & Bozdag, S. (2019). miRDriver: A Tool to Infer Copy Number Derived miRNA-Gene Networks in Cancer. In Proceedings of the 10th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics (pp. 366–375). New York, NY, USA: ACM. https://doi.org/10.1145/3307339.3342172

Dursun, C., Shimoyama, N., Shimoyama, M., Schläppi, M., & Bozdag, S. (2019). PhenoGeneRanker: A Tool for Gene Prioritization Using Complete Multiplex Heterogeneous Networks. In Proceedings of the 10th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics (pp. 279–288). New York, NY, USA: ACM. https://doi.org/10.1145/3307339.3342155

2018

Do, D., & Bozdag, S. (2018). Cancerin: A computational pipeline to infer cancer-associated ceRNA interaction networks. PLoS Computational Biology14(7), e1006318. https://doi.org/10.1371/journal.pcbi.1006318

2017

Ready, D., Yagiz, K., Amin, P., Yildiz, Y., Funari, V., Bozdag, S., & Cinar, B. (2017). Mapping the STK4/Hippo signaling network in prostate cancer cell. PLoS ONE12(9). https://doi.org/10.1371/journal.pone.0184590

Baur, B., & Bozdag, S. (2017). ProcessDriver: A computational pipeline to identify copy number drivers and associated disrupted biological processes in cancer. Genomics109(3–4), 233–240. https://doi.org/10.1016/j.ygeno.2017.04.004

Muñoz-Amatriaín, M., Mirebrahim, H., Xu, P., Wanamaker, S. I., Luo, M., Alhakami, H., … Close, T. J. (2017). Genome resources for climate-resilient cowpea, an essential crop for food security. Plant J, 89(5), 1042–1054. https://doi.org/10.1111/tpj.13404

2016

Baur, B., & Bozdag, S. (2016). A Feature Selection Algorithm to Compute Gene Centric Methylation from Probe Level Methylation Data. PloS One11(2), e0148977. https://doi.org/10.1371/journal.pone.0148977

2015

Baur, B., & Bozdag, S. (2015). A canonical correlation analysis-based dynamic bayesian network prior to infer gene regulatory networks from multiple types of biological data. Journal of Computational Biology: A Journal of Computational Molecular Cell Biology22(4), 289–299. https://doi.org/10.1089/cmb.2014.0296

LaDisa, J. F., Bozdag, S., Olson, J., Ramchandran, R., Kersten, J. R., & Eddinger, T. J. (2015). Gene Expression in Experimental Aortic Coarctation and Repair: Candidate Genes for Therapeutic Intervention? PLoS ONE10(7). https://doi.org/10.1371/journal.pone.0133356

Muñoz-Amatriaín, M., Lonardi, S., Luo, M., Madishetty, K., Svensson, J. T., Moscou, M. J., … Close, T. J. (2015). Sequencing of 15,622 gene-bearing BACs clarifies the gene-dense regions of the barley genome. The Plant Journal, 84.1: 216-227.. https://doi.org/10.1111/tpj.12959

Pradeep, P., Povinelli, R. J., Merrill, S. J., Bozdag, S., & Sem, D. S. (2015). Novel Uses of In Vitro Data to Develop Quantitative Biological Activity Relationship Models for in Vivo Carcinogenicity Prediction. Molecular Informatics, 34(4), 236–245. https://doi.org/10.1002/minf.201400168

2014

Baysan, M., Woolard, K., Bozdag, S., Riddick, G., Kotliarova, S., Cam, M. C., … Fine, H. A. (2014). Micro-Environment Causes Reversible Changes in DNA Methylation and mRNA Expression Profiles in Patient-Derived Glioma Stem Cells. PLoS ONE9(4). https://doi.org/10.1371/journal.pone.0094045

Bozdag, S., Li, A., Baysan, M., & Fine, H. A. (2014). Master regulators, regulatory networks, and pathways of glioblastoma subtypes. Cancer Inform13(Suppl 3), 33–44. https://doi.org/10.4137/CIN.S14027

2013

Wuchty, S., Vazquez, A., & Bozdag, S. (2013). Genome-wide associations of signaling pathways in glioblastoma multiforme. BMC Medical Genomics6, 11. https://doi.org/10.1186/1755-8794-6-11

Bozdag, S., Li, A., Riddick, G., Kotliarov, Y., Baysan, M., Iwamoto, F. M., … Fine, H. A. (2013). Age-Specific Signatures of Glioblastoma at the Genomic, Genetic, and Epigenetic Levels. PLoS ONE, 8(4). https://doi.org/10.1371/journal.pone.0062982

Bozdag, S., Close, T. J., & Lonardi, S. (2013). A Graph-Theoretical Approach to the Selection of the Minimum Tiling Path from a Physical Map. IEEE/ACM Trans Comput Biol Bioinformhttps://doi.org/B886D413-EA51-4D69-9095-CC2D5FEF04AB

Lonardi, S., Duma, D., Alpert, M., Cordero, F., Beccuti, M., Bhat, P. R., … Close, T. J. (2013). Combinatorial pooling enables selective sequencing of the barley gene space. PLoS Comput Biol, 9(4), e1003010. https://doi.org/10.1371/journal.pcbi.1003010

Sahu, S. N., Lewis, J., Patel, I., Bozdag, S., Lee, J. H., Sprando, R., & Cinar, H. N. (2013). Genomic analysis of stress response against arsenic in Caenorhabditis elegans. PLoS One8(7), e66431. https://doi.org/10.1371/journal.pone.0066431

2012

Baysan, M., Bozdag, S., Cam, M. C., Kotliarova, S., Ahn, S., Walling, J., … Fine, H. A. (2012). G-cimp status prediction of glioblastoma samples using mRNA expression data. PLoS One7(11), e47839. https://doi.org/10.1371/journal.pone.0047839

Sahu, S. N., Lewis, J., Patel, I., Bozdag, S., Lee, J. H., LeClerc, J. E., & Cinar, H. N. (2012). Genomic analysis of immune response against Vibrio cholerae hemolysin in Caenorhabditis elegans. PLoS One7(5), e38200. https://doi.org/10.1371/journal.pone.0038200

Wuchty, S., Arjona, D., Bozdag, S., & Bauer, P. O. (2012). Involvement of microRNA families in cancer. Nucleic Acids Res40(17), 8219–8226https://doi.org/10.1093/nar/gks627

2010

Kotliarov, Y., Bozdag, S., Cheng, H., Wuchty, S., Zenklusen, J.-C., & Fine, H. A. (2010). CNAReporter: a GenePattern pipeline for the generation of clinical reports of genomic alterations. BMC Medical Genomics3, 11. https://doi.org/10.1186/1755-8794-3-11

Bozdag, S., Li, A., Wuchty, S., & Fine, H. A. (2010). FastMEDUSA: a parallelized tool to infer gene regulatory networks. Bioinformatics26(14), 1792–1793. https://doi.org/10.1093/bioinformatics/btq275

Li, A., Bozdag, S., Kotliarov, Y., & Fine, H. A. (2010). GliomaPredict: a clinically useful tool for assigning glioma patients to specific molecular subtypes. BMC Med Inform Decis Mak10, 38. https://doi.org/10.1186/1472-6947-10-38

2009

Bozdag, S., Close, T. J., & Lonardi, S. (2009). A compartmentalized approach to the assembly of physical maps. BMC Bioinformatics, 10, 217. https://doi.org/10.1186/1471-2105-10-217

Close, T. J., Bhat, P. R., Lonardi, S., Wu, Y., Rostoks, N., Ramsay, L., … Waugh, R. (2009). Development and implementation of high-throughput SNP genotyping in barley. BMC Genomics10, 582. https://doi.org/10.1186/1471-2164-10-582

2008

Bozdag, S., Close, T., & Lonardi, S. (2008). Computing the minimal tiling path from a physical map by integer linear programming. Algorithms in Bioinformatics, 148–161.

2007

Bozdag, S., Close, T. J., & Lonardi, S. (2007). A Compartmentalized Approach to the Assembly of Physical Maps. In IEEE International Conference on Bioinformatics and Bioengineering (pp. 218–225). https://doi.org/10.1109/BIBE.2007.4375568